DEScribe connection issues

A few points if you're having trouble connecting to DEScribe.

Be sure to allow sufficient time for drivers to install (if applicable) when a new product is connected via USB.
The Sabertooth or Syren must be "on" to work with DEScribe. Verify this by the on-board Status LED.
For USB Sabertooth (2x32), verify that your micro USB cable is capable of data transfer or syncing. Charge-only cables will not work.
For non-USB enabled motor drivers, be sure that the converter you are using is specified as "USB to TTL." RS-232 will not work, and also can cause damage to the motor driver.
It does not hurt to swap the Tx/Rx lines if you are still having difficulties, as some converters may not be clearly labeled. Do not swap the ground and power lines.